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University Of South Alabama Researchers Study Progression Of Deadly Lung Syndrome

| March 19, 2019 @ 5:00 am

By University of South Alabama

Researchers at the University of South Alabama College of Medicine have developed a pre-clinical model for Acute Respiratory Distress Syndrome (ARDS), a progressive disease that occurs in critically ill patients. A team led by Dr. Diego F. Alvarez and Dr. Jonathon P. Audia published the results of this NIH/NHLBI-sponsored study in the March 11 online edition of Pulmonary Circulation.

ARDS has a mortality rate of 40 to 60 percent in patients who develop the disorder, which is characterized by worsening lung function. Typically ARDS develops as a result of community- and hospital-acquired pneumonia and patients are treated in an intensive-care setting.

“Right now there are no therapies to treat these patients once ARDS develops other than supportive care,” said Audia, associate professor of microbiology and immunology. “Our goal is developing comprehensive models to understand the disease progression and how it resolves, and then ultimately being able to use this model to test new therapies.”

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